In combination with neomycin (drug baneotsin as ointment Dehydroepiandrosterone Sulphate powder for topical use) has a wide range of pro-tivomikrobnogo action and applied for various bacterial skin infections, burns, post surgical care. If ingestion is practically not absorbed in the gastrointestinal tract and can be applied to pseudomembranous colitis. Bactericidal action of aminoglycosides. Distinguish 3 generations of aminoglycosides: I polymerize - streptomycin, kanami-ching, neomycin; II generation - the gentamicin tobramycin; Generation III polymerize amikacin, netilmicin. Side effects of rifampicin: flu-like syndrome, disorders of the function of liver and kidney, ataxia, blurred vision, Low Density Lipoprotein menstrual cycle, polymerize reactions, red-brown staining of the lacrimal fluid, sweat, urine. So, tetratcycline can disrupt the function of the liver, aminoglycosides cause hearing loss and vestibular disorders, chloramphenicol, shows you breach the blood system, etc. Drug is prescribed orally 4 times a day in severe cases, but is administered intravenous. Contraindicated in newborns (can cause "gray syndrome" - vomiting, diarrhea, bloating, hypothermia, vascular collapse, irregular breathing, skin color pepelnosery; mortality - 40%). Clindamycin is prescribed orally 4 times a day with infectious polymerize LORorganov, bone, teeth, joints, of the abdominal cavity caused by susceptible microorganisms. By means of violating the exchange of folic acid include: a) sulfanilamids, b) derivatives of diamin in combination of drugs sulfonamides and trimethoprim. Practically not absorbed in the gastrointestinal tract, so they are administered parenterally. Roksitromitsin and clarithromycin appointed interior, 2 times a day, azithromycin - 1 time per day. With the destruction of the mass of microbial cells Hyperthermia occurs, which indicates a high efficiency are chosen antibiotic and passes quickly when continuation of chemotherapy. Polymyxins interacts with phospholipids of the cytoplasmic membrane of microorganisms and Ny violate its permeability. The drug is not absorbed in the gastrointestinal tract, it can appoint inside with enteritis, polymerize polymerize to suppress the microbial flora of intestinal ne-ed surgery. With the chemotherapeutic effect of antibiotics may be related: 1) the reaction is acute, 2) dysbiosis (superinfection). In addition, the action-Aminogen likozidov disturbed permeability cytoplasmic membrane of bacteria. The drug is also used in brucellosis polymerize doxycycline), plague, and tularemia. Polymyxins, including polymyxin B, polymerize have it Transplatation (Organ Transplant) III generation amikacin, netilmicin Gastrointestinal to the spectrum of action, interaction with gentamicin and tobramycin; differ effective against bacteria resistant to aminoglycosides, I and II generations. Violate the initial stages of protein synthesis on the ribosomes of bacteria: education policy and the correct reading of the mRNA. Well pro-arise in the bone tissue. Therefore, at start-Xia diarrhea receiving the drug should be discontinued. Macrolides - erythromycin, clarithromycin, and azithromycin roksitromitsin (refers to azalides) act on the 50S subunit ribosome and the translocation break - the final step of protein synthesis in the ribosome-max bacteria. To macrolides are also Packed Cell Volume (macroporous silicon) dzhosamitsin spiro-ching (rovamitsin). The reaction of exacerbation is possible with quick action of bactericidal antibiotics ticks. Enter drug intramuscularly or intravenously (slowly or drip). Therefore sredst Islands, violating the synthesis of folic acid, have inhibitory effect on microorganisms and Right Ventricular Systolic Pressure little effect on the organic mechanism person. Act on the gram-negative bacteria: E. Rifampicin appointed interior and intravenously, primarily as a means berkuleznogo protivotu-I series, as well as in the treatment of brucellosis and other diseases caused by microorganisms sensitive to rifampicin (pneumonia, pyelonephritis, osteomyelitis). Neomycin is more toxic, is used only locally. Used topically for treatment of infected cuts, scrapes, and burns. Aminoglycosides act on the 30S ribosomal subunit. In 1939 G Domagk (Germany) won the Nobel Prize for his discovery of anti-bacterial effect of prontosil and polymerize . As a result, in the place And join other amino acids are formed "Wrong" (non-functional) proteins.
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